SCH-23390 hydrochloride ole D4 Soblidotin (Auristatin PE) is a

Soblidotin (Auristatin PE) is a synthetic analog of dolastatin 10 which inhibits the growth of several tumoral cell lines and induces caspase-3-dependent apoptosis

Formula: C45H72N14O10

2-b]furan-3-ol

and endothelial TEK tyrosine kinase (Tie2))

12-dihydroxyabieta-8

SCH-23390 hydrochloride ole D4 Soblidotin (Auristatin PE) is aSCH 23390 hydrochloride (R (+) SCH 23390 hydrochloride) is a potent and selective dopamine D1 like receptor antagonist with Kis of 0. 2 nM and 0. 3 nM for the D1 and D5 receptor, respectively. SCH 23390 hydrochloride is a potent and high efficacy human 5 HT2C receptor agonist with a Ki of 9. 3 nM. SCH 23390 hydrochloride also binds with high affinity to the 5 HT2 and 5 HT1C receptors. SCH 23390 hydrochloride inhibits G protein coupled inwardly